Lyari, one of the oldest neighbourhoods of Karachi, has been the site of ongoing violence for most of the past two decades. This paper explores the impacts of the ongoing conflict involving criminal gangs, political parties and state security forces. Residents have adopted tactics and strategies ranging from negotiation to active resistance in response to the varied forms of everyday violence. Specifically focusing on street protests between 2012 and 2014, it evaluates the possibilities and limitations of protest in the context of urban violence. More broadly, it argues that studies of urban violence need to move away from viewing the urban poor as exclusively clientelistic or insurgent. It argues that acts of resistance in the form of protest are constrained, determined by, and productive of particular configurations of power.